Is the Sav1866 model of CFTR protein the most closer to the human one?

Sediki Fatima Zohra @Sediki-Fatima-Zohra

26 May 2015 1 3K Report

Do you think that the Sav1866 model of CFTR protein is the most closer to the human one, if we are looking to explore CFTR mutations with an in silico study?

Farruk Lutful Kabir

I think, you may not use this model for complete structural analysis of CFTR since the putative molecule misses some structures.

Have a look at this paper.

Hope it will help you understand.

Article The Cystic Fibrosis Transmembrane conductance Regulator (CFT...

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