in a recent article PRF was used in a case report to replace dental pulp but with limitations. In decidual teeth, in my clinical practice, calcium hydroxide and portland cement like Biodentine (septodont) are the gold standard to formocrezol.
Studies have shown that PRF can be used as a scaffolding material in an infected necrotic immature tooth for pulpal regeneration and tooth revitalization. Studies that measure their success in primary teeth do not yet exist (as far as I have been able to look) since there are only a few case reports; But it has been found to use the PRF in pulpotomies of permanent molars. In a clinical trial conducted by Kumar, he mentions that the use of MTA is better than the PRF in pulpotomies of permanent molars with irreversible pulpitis, whereas in a clinical trial performed by Keswani he mentions that PRF is better than MTA in pulpotomies of permanent teeth With incomplete root development.
I hope you have answered something to your question. Best regards
Regenerative endodontics has some clinical cases with success, however in deciduous teeth that after a caries process need to be restored, what is the goal of getting a dentin bridge?
A scaffold made of fibrin and the growth factors obtained from platelets may be a culture broth.
One of the points that must be taken into account in the clinical procedure of pulpotomy is that of bacterial contamination. The use of formocresol is not only intended to fix the remaining pulp of the pulp, but also to eliminate some traces of Bacterial contamination , which is also achieved with the use of calcium hydroxide and with the MTA.
It is clinically evaluated with better success rate. but very few have been documented in case of primary teeth .
we have one reference article ,quite interesting document by Dr.Damle dated in 2004 Published by Indian society of Pedodontics and Preventive Dentistry.
Below is the title of the article Hope this helps...
Comparative evaluation of lyophilized freeze dried platelet derived preparation with calcium hydroxide as pulpotomy agents in primary molars.Isppd 2004;22(1):24-9