In other words, is there a chemical impact caused by THC which could be activating neural correlates in the insular cortex (ic) of the brain?
The increase in the sensory activating system-dopamine caused by THC as seen in previous researches (doi: 10.1038/nature20153) can be damaging the neural correlates between regions of the brain associated with feelings.
The IC is not the only part of the brain that contributes to feelings, the hypothalamus and the brainstem do, however, the addictive behavior of individuals is mainly caused by problems to the ic.
What are your insights?
Almost certainly but probably not in the way that you believe; paranoia, as a variety of psychosis is a language structure. In those individuals with a psychotic underlying language structure, a trigger for a florid episode, which might be erotomanical, catatonic or paranoid, could be promotion, pregnancy or THC. You could look at my book, Introducing Lacanian Clinical Technique. Of course there will be much in common between neurones and underlying language structure but one is more accessible than the other.
So no, THC is not a simple cause of paranoia but it certainly can trigger obvious paranoia in someone whose paranoia was previously hidden. By analogy: someone who has particular type of immune system would produce an allergic response to penicillin, if they took it. So long as that person doesn't take penicillin their type of immune system remains hidden.
Is induction causal? In part, just as a gun's trigger being pulled is in part causal but the trigger or induction does not describe the most important part of the structure.
Could the variety of chemicals in cannabis be allowing for some to pass through the blood-brain membrane which can contribute to a higher alteration of feelings than that observed from other addictive chemicals?
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