Is there any chance that dyslipidemia has any causative chance for generating neurodegeneration?
Take a look at these articles
Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associations. Christiane Reitz. J Alzheimers Dis. 2012; 30(0 2): S127–S145.
Dyslipidemia and the Risk of Alzheimer’s Disease. Christiane Reitz. Curr Atheroscler Rep. 2013 Mar; 15(3): 307.
Cholesterol, Statins, and Dementia: What the Cardiologist Should Know. Brett L. Wanamaker et. all. Clin Cardiol. 2015 Apr; 38(4): 243–250.
Alzheimer patients who have all their vascular risk factors well-managed have been shown to decline less rapidly than those who do not keep their hypertension, diabetes, or hyperlipidemia under good control (Deschaintre et al, Neurology 2009;73 (9): 674-680).
Yes, especially after chronic exposure to continuously fluctuating plasma lipid levels.
Dear Sayam,
Thanks for an interesting question. As many of our colleagues has discussed that dyslipidemia is a modifiable risk factor in the development of dementia and cardiovascular diseases. Mr Sedat has already provided the details of few articles.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564220/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409455/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689537/
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