What I know is that some plant extracts have anti-microbial properties and this is the reason why there is an orientation to use instead of medicines to reduce the problem of exacerbating resistance to antibiotics, so I think it possible.
Some medicinal plants such as Veronica biloba extracts shows good antifungal and antimicrobial activity. And can be used to treat bacterial and fungal infections.
Similarly, the methanolic extract of caryophllus aromatics shows anti staphylococcus aureus (bacteria) activity and is also effective against many other bacteria.
Natural extracts have been used as antimicrobial agents, and extracts of the rhizomes of the dragon's blood plant ... https://www.mdpi.com/2076-3417/8/12/2516/pdf
Antimicrobial Properties and Mechanism of Action of Some Plant Extracts Against Food Pathogens and Spoilage Microorganisms https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066648/
Ethanolic and water extracts of roselle (Hibiscus sabdariffa), rosemary (Rosmarinus officinalis), clove (Syzygium aromaticum), and thyme (Thymus vulgaris) have antibacterial and antifungal effects on some food pathogens and spoilage microorganisms. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066648/