Is it possible to establish a osteomyelitis mouse model using human bone?

Amanda dos Santos Cavalcanti @Amanda-Cavalcanti

22 November 2024 1 858 Report

Has anyone tried to make a model of ectopic osteomyelitis in a nude mouse using patient-derived xenografts (fragments of infected bone from patients)?

Xun Fang

According to the mechanism of infection, osteomyelitis can be divided into two categories: blood osteomyelitis; non-blood osteomyelitis, which can be caused by invasion of adjacent infection sites or infection of bone tissue directly. Live bone xenografts may will cause GVHD.

In our company have osteomyelitis mouse model，if you need more detail please send me mail.

[email protected]

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