Hello Everyone
I would like to do a reaction between a amine compound (Michael donor) and vinyl sulfonated polysacchride (Michael acceptor). So is it possible to do a click reaction with use of a base catalyst if so what kind of catalyst should I use?, and if anyone can recommend a reaction protocol .
Protocol, you will need to search in the literature on your own! Technically it will go!
Dear Castro,
Here are some options, which can if nothing else, lead you to the optimal conditions for your experiment.
Crystals 2020, 10, 643; doi:10.3390/cryst10080643
Tetrahedron Letters 48 (2007) 9040–90439041
Chem. Lett. 2016, 45, 1356–1358 | doi:10.1246/cl.160772
Best of luck in your work,
Ivana Jevtić
Michael addition reaction between Vinyl sulfones and Amines will work
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