We are trying to design a clinical trial on type 2 diabetes patients. The main data that we want to assess include FBS, 2hpp, HbA1c, insulin, and HOMA-IR. Also, we will assess the lipid profile and stress oxidative indices (MDA and TAC). The problem is that we could not find any similar study to determine the sample size. In this situation is it possible to use the Cohen formula? If not what is the right way for determining the sample size?
You can use G*Power calculation to determine your sample size without worrying if the sample size is under the attribution of statistical significance. G*Power is a common sample calculation particularly in setting up a clinical trial.
Please check out this publication for more details:
Use of G*Power Software | SpringerLink by:
Verma J.P., Verma P. (2020) Use of G*Power Software. In: Determining Sample Size and Power in Research Studies. Springer, Singapore. https://doi.org/10.1007/978-981-15-5204-5_5
Hope it would be helpful and all best luck!
You can use G*Power calculation to determine your sample size without worrying if the sample size is under the attribution of statistical significance. G*Power is a common sample calculation particularly in setting up a clinical trial.
Please check out this publication for more details:
Use of G*Power Software | SpringerLink by:
Verma J.P., Verma P. (2020) Use of G*Power Software. In: Determining Sample Size and Power in Research Studies. Springer, Singapore. https://doi.org/10.1007/978-981-15-5204-5_5
Hope it would be helpful and all best luck!
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