There are various aloe species growing in a particular location with a definite pattern of distribution. One particular species grows exceptionally on the rock cliffs were there is limited presence of other vegetation. Other aloe species in the same area grow at the foot of the rock.
Quite possible, but you need to test for the constituents using various chemical tests. Here you should target the anthracene glycosides which are the major constituents. Any variation in the content of aloin, barbaloin, aloe-emodin, isobarbaloin can be vital as this are the major contributors to its purgative activity. Other than these the hormones, chromones, carbohydrates, enzymes, proteins and vitamins which altogether have been held responsible for its antioxidant, antiallergic, antiinflammatory and immunomodulatory activities might also prove useful for your analysis. Extrinsic factors are a major cause of variability in drug activity.
Variations are possible as the composition of secondary metabolites depend on soil nature, vaialbility of water and nutrients, sunlight, microbial attacks etc
Obviously according to species there will be definitely variations.
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