Is it possible for spin-column purified RNA to have a 260/280 ratio above 2.0?

25 February 2019 0 5K Report

I extracted total RNA from plant tubers using Macherey-Nagel RNA extraction kit. Upon Nanodrop examination I got following results;

Nucleic acid concentration: 15.5 ng/uL

A260: 0.39

A280: 0.10

260/280: 4.03

260/230: 0.02

Sample type: RNA

Factor: 40.00

Why is 260/280 ratio so high? What could be possible reason and how can I rectify it?

Thanks

Yugendran

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