Is it possible for lipid nanoparticles to merge with extracellular matrix of biofilms?

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Marwan M. A. Mohammed

Ideally, Yes, lipid nanoparticles (LNPs) can merge with the extracellular matrix (ECM) of biofilms. Their ability to do so depends on properties like size, surface charge, and composition. Positively charged or hydrophobic LNPs may adhere more effectively to ECM components. LNPs can penetrate biofilms through aqueous channels and may release their load gradually, potentially disrupting the biofilm structure or delivering antimicrobials.

Gerry/Gerre A Quinn

Thanks Marwan M. A. Mohammed