According to TreeFam database methadology, a gene family is a group of genes that descended from a single gene in the last common ancestor of a considered species.
Hi,
have a look at this paper:
http://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-015-0570-8
Thank you Ludovic....I read the paper...so do you mean that we can call gene families more or less as protein domains also?
I think this might help https://www.biostars.org/p/86123/
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