Does anyone know - based on scientific research or clinical experience - whether EMDR is incompatible with an anti-depressive? An acquaintance, Mrs. C., is on 15 mg Mirtazapine (almost the minimum dosage) to keep her extreme generalized anxiety somewhat between limits. In the past she had suffered a brief psychotic episode. Her therapist (Mrs. C. is still on the waiting-list) claims that being medication-free is an absolute condition for EMDR to be effective. To me the risk seems too big.