Hi, I have Bipolar 1 and managed it well with Lithium (400mg/night). My Nephrologist has prescribed Amlodipine for high blood pressure. I have Stage 4 CKD due to long-term Lithium use, but it is important to lower my BP. Can Amlodipine cause psychosis?
Amlodipine is generally considered safe to take with lithium, especially for managing high blood pressure in individuals with bipolar disorder like yourself. There isn't a known interaction that typically causes psychosis between these two medications. However, it's crucial to monitor any potential side effects closely, as everyone's response can vary.
Given your stage 4 chronic kidney disease (CKD) due to long-term lithium use, it's understandable that managing your blood pressure is essential. Amlodipine is a calcium channel blocker that is often preferred in such cases because it can be used cautiously in patients with impaired kidney function.
To ensure safety and effectiveness, it's vital to keep your healthcare providers well-informed about all medications you are taking, including over-the-counter and supplements. They can monitor for any adverse effects and adjust your treatment plan as needed to maintain your health and manage both your bipolar disorder and CKD effectively.
Yes, they can be used together, but under medical supervision with close monitoring of lithium levels and kidney function.
Amlodipine is classified as a low brain penetration calcium channel blocker, meaning it doesn't readily cross the Blood Brain Barrier.
The brain penetrant CCBs are considered to reduce the risk of neuropsychiatric disorders.
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