Insulin unit conversion method ?

02 January 2024 1 7K Report

"Using the Insulin unit conversion method (1 µIU/mL = 0.04 ng/mL), can this be applied to measurements taken by ELISA (pg/mL) rather than ECLIA (Electrochemiluminescence Immunoassay)? This particular ELISA (MILLIPLEX Human Metabolic Hormone Panel, www.merckmillipore.com) is not a commonly used method in clinical practice."

Robert Adolf Brinzer

You may find this article useful (Article Insulin Units and Conversion Factors: A Story of Truth, Boot...

). Basically depending on the insulin preparation and amino acid sequence (analogues) you can get variations in potency (IU) for the same mass (SI).

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