The extraction efficiency of 2,3-butanediol increased from 20.8% to 76.59% with a solvent-to-feed ratio of 0.5 to 1.5. If 2,3-BD concentration increased, such a high recovery of 76.59% could be obtained or not.
The extraction efficiency of 2,3-butanediol depends on several factors, such as the type and concentration of the solvent, the salt, the pH, the temperature, and the initial concentration of 2,3-butanediol in the feed. According to some studies, increasing the initial concentration of 2,3-butanediol in the feed can improve the extraction efficiency, but it may also increase the solvent consumption and decrease the selectivity[1-2]. Therefore, there is a trade-off between the extraction efficiency and the process economics. To optimize the extraction process, it is necessary to consider all these factors and find the best operating conditions for a given system.
Some references that provide more details about the extraction of 2,3-butanediol from fermentation broth are:
- Purification of 2,3-butanediol from fermentation broth: process development and techno-economic analysis by Gregorius Rionugroho Harvianto et al., published in Biotechnology for Biofuels in 2018[1].
- Extraction of 2,3-Butanediol with Aqueous Two-Phase Systems Formed by Water-Miscible Organic Solvents and Inorganic Salts by Michiaki Matsumoto et al., published in Solvent Extraction Research and Development, Japan in 2014[2].
- Aqueous two-phase extraction of 2,3-butanediol from fermentation broth by Zhihao Sun et al., published in Biotechnology Letters in 2009[3].
- Liquid - Liquid Extraction of 2, 3-Butanediol from Fermentation Broth by S. M. Mousavi et al., published in Iranian Journal of Chemistry and Chemical Engineering in 2007[4].
Article Purification of 2,3-butanediol from fermentation broth: Proc...
http://www.solventextraction.gr.jp/serdj/jurnalpdf/vol21%282%29/21_181.pdf
Article Aqueous two-phase extraction of 2,3-butanediol from fermenta...
https://www.ijcce.ac.ir/article_5990.html
Article Production of 2-butanol through meso-2,3-butanediol consumpt...
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