Which is beneficial management of covid 19.
Immunomodulactors or Immunosuppressive agent like steroids or both.
And their mechanism of action if effective in covid 19
Covid-19 is usually a mild self-limiting illness that does not require any treatment.
Current evidence based medicine is based on the presumption of significance when P
Immunomodulators are more effective and beneficial in the management of COVID 19
Immunomodulactors and immunosuppressive in covid
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Depending on the situation (disease course), both immunomodulators and immunosuppressants can be used.
" Critically ill patients require careful assessment to determine if either of these may be beneficial. "
Rajkumar Rajendram
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https://www.researchgate.net/post/Why_arent_drugs_implementing_activation_of_cholinergic_anti-inflammatory_pathway_cholinomimetics_a7nAChR_agonists_used_in_treatment_of_COVID-19
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Why aren't drugs implementing activation of cholinergic anti-inflammatory pathway (cholinomimetics, α7nAChR agonists, etc.) used in treatment of COVID-19?
It was found that activation of cholinergic anti-inflammatory pathway reduces the concentration of pro-inflammatory cytokines in the blood and organs during sepsis, and various infectious diseases, while significantly reducing mortality.
https://en.wikipedia.org/wiki/Cholinergic_anti-inflammatory_pathway#:~:text=The%20cholinergic%20anti%2Dinflammatory%20pathway,and%20regulates%20the%20inflammatory%20response.
(see^ https://www.researchgate.net/profile/PF_Zabrodskii/research
see^ https://pubmed.ncbi.nlm.nih.gov/?term=Zabrodskii+P.F. )
Article [Effect of armin on nonspecific resistance factors of the bo...
Article Variation in antiinfectious nonspecific resistance of the or...
Article P.F. Zabrodskii. Effect of acetylcholine on mortality of mic...
Article [The effect of anabasine on mortality and concentration of p...
Article Effect of α7n-Acetylcholine Receptor Activation and Antibodi...
Article P. F. Zabrodskii, M. S. Gromov, V. V. Maslyakov. Combined Ef...
Article Effects of reversible inhibition of cholinesterase and nicot...
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Why aren't drugs implementing activation of cholinergic anti-inflammatory pathway (cholinomimetics, α7nAChR agonists) used in treatment of COVID-19?
Along with other drugs!
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I write about the way, along with others, as a complement to them. But there is no vaccine yet. But there's a cytokine storm.
https://www.newscientist.com/term/cytokine-storm/
https://en.wikipedia.org/wiki/Cytokine_release_syndrome
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Article Immunomodulatory drugs: Oral and systemic adverse effects
Article Immunomodulatory drugs: Oral and systemic adverse effects
https://www.newscientist.com/term/cytokine-storm/
https://en.wikipedia.org/wiki/Cytokine_release_syndrome