T50 is the time to 50% dissolved of the product (minutes or hours?).  The k is the rate constant describing the release rate (no units provide, but is likely first order, but could be zero order).  Correlation coefficient tells how good the line fits the data, with a 1 being perfect (0.99 and above is excellent).  The n may be a standard deviation term.

Thanks  dr.Charles Collins sir..!

how to determine release exponent n,k and T50.

In this n- Release exponent, 

If n-value 0.5 means drug transport Fickian diffusion mechanism.

0.5 < n-value(0.99) drug transport Non-Fickian transport mechanism that is super case II transport and  function of the time tn-1.

Dear Mr Giram,

Software is available to calculate all these values from the release data. 

However, you can also calculate all these values from plot.

T50: Generate Cumulative drug release vs time plot. Determine time corresponding to 50 % cumulative drug release.

n, k: Both are associated with korsmeyer peppas equation, i.e., (Mt/Mα)=  ktn), where Mt and Mα are drug release at time t and infinity. Plot log (Mt/Mα) vs log t. the intercept and slope will be log K and n respectively.

Regards

Srimanta