Hello all, I am currently in the process of conducting a chromosomal aberration test using whole blood samples to test toxicity of nanoplastics, and I have a question regarding the protocol. In the context of this assay, should I replace the media after 48 hours of incubation or to add testing material directly to the incubated media. Could you kindly provide clarification on this matter?

Your expertise and guidance in this area would be greatly appreciated. Thank you in advance for your assistance.

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