I am looking for articles comparing Abeta in primary culture of neurons from APPwt transgenic mice compared to mutant APP transgenic mice. An idea ?

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Gunnar Keppler Gouras

We have numerous papers on this, initially with heterozygous Tg2576 compared to wild type embryos from the same mother, but more recently also with AP/PS1 transgenics from Jackson Labs. Tg2576: Takahashi RH et al. 2004; Almeida CG et al. 2005; Almeida CG et al. 2006; Tampellini D et al., 2007; etc.; APP/PS1 transgenics: Klementieva O et al., 2017.

Karine Laulagnier

Thanks a lot for your answer Gunnar. I will carefully read your papers.