I am doing alkane oxidation using m-CPBA as oxidant in DCM. How can I remove the oxidant and its corresponding acid (m-CBA) from my reaction mixture? I also did aqueous work-up using NaHCO3 and also did a short silica/alumina colum but despite that everytime i get some solid which is acid although the desired products are alcohol or ketone (liquid).
Good for quenching mCPBA IMHO. Na2S2O5 (sodium metabisulfite) is the most selective for reducing peroxides. It does not have any nucleophilic behavior. Prepare a chosen salt above in water (anywhere from 5% to saturated), test your peroxide content with starch paper.
https://www.researchgate.net/post/How_does_one_quench_the_excess_MCPBA_in_an_epoxidation_reaction
Kindly follow the instructions outlined at
http://chem.chem.rochester.edu/~nvd/pages/workup.php?page=mcpba
The problems in removing m-cpba and its corresponding acid .MCBA is used as a oxidizing reagent and the byproduct of the reaction is m-chlorobenzoic acid. It is soluble in aq. NaHCO3. However , your product is not soluble. The solid product is different acid. Identify by IR,PMR, CMR and Mass data.
- Badges
- Science topic
- Similar topics
- Chemistry
- Sulfites
- Inorganic Chemistry
- Acids