Dear Ebrahim,

Are you using metal or glass electrodes? Unstable baseline can be due to many factors: such as bad grounding or lack of it, blocked tip or high resistance at the tip of your electrode, large (broken) electrode tip. In the past I have done extra cellular recordings from retina using glass electrodes (see below for details)

best wishes, Refik

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Dear Refik,

I am using glass electrodes. I will check the tip of electrodes and grounding.

Thank you very much.

Best,

Ebrahim