The significance of paying constant attention (i.e being mindful) to what one wants or having a clear purpose in life (reminding us constantly where we are heading). This mindfulness can be contrasted with being robotic or switching the autopilot on to get our routine tasks completed. When we are mindful of what we do, our neural networks strengthen and grow, enabling us to learn and develop wisdom.
http://www.abc.net.au/news/health/2017-07-19/change-your-mindset-to-change-your-life/8719546
I like Dr. Alia Crum's presentation on "Change Your Mindset, Change the Game." Positive mindset/expectations can make a big difference in our health, wellbeing, and life.
In his classic book Persuasion and Healing, Dr. Jerome Frank talked about similar concepts about the effectiveness of psychotherapy.
https://www.youtube.com/watch?v=0tqq66zwa7g
https://books.google.com/books/about/Persuasion_and_Healing.html?id=vnMBQiOyTn0C
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