12 December 2016 3 506 Report

When determining sample size we require population proportion (p) for a dichotomous outcome that to be measured (at 95% CI , 3% error ).

If the proportion (p) is unknown a conservative estimate of .5 assumed. sometimes pilot study conducted to find a value for the proportion (p). If there is previous study we can take values for the proportion (p) from there.

One wants to study vaccination pattern among nurses (yes /no). There are three studies where vaccination rate was 47%, 52% and 57% . Now which values should be chosen for the proportion (p)? 0.47 or 0.52 or 0.57 or can one simply go for an intermediate 0.5?

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