I have no experience with the Thermotropic Liquid Crystalline materials, but I know that there are special chambers for XRD measurements at high temperature, high pressure, low temperature, varying humidity etc. For instance: https://www.bruker.com/fileadmin/user_upload/8-PDF-Docs/X-rayDiffraction_ElementalAnalysis/XRD/Brochures/Non-ambient_brochure_DOC-B88-EXS023_V1_low.pdf