Hello,
Nowadays, it is not possible to directly examine the structural changes at the brain cell level (e.g., neurogenesis). Thus, it is still unclear the actual effects of physical exercise on brain derived neurotrophic factors release (BDNF). However, the scientific technological progress has allowed to indirectly study the brain structures and changes at a more macroscopic level.
In order to study the relationship between exercise and BDNF changes in children/adolescent population, what are the main feasible, non-invasive methods?
Microstructural MRI changes (diffusion tensor to study white matter and voxel based morphometry to study regional brain volumes, for example) should be correlated with BDNF levels pre- and post-exercise
Dear Antonio
Its possible by means of Microstructural MRI changes to study regional brain volumes. on the other hand, you can consider it through the based behavioral observation .
let me know if more help needed.
kind reards
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