Saadia Ijaz

it is not possible to set up GPU acceleration for Schrödinger Maestro MD simulations on Windows 11. Schrödinger's GPU-accelerated molecular dynamics simulations, including those run through Desmond, are only supported on Linux operating systems. For Windows users, the recommended approach is to run Maestro locally on your Windows machine for visualization and job setup, but submit computationally intensive tasks like MD simulations to a Linux-based computing cluster or cloud service that has the necessary GPU hardware and software configuration.

Thanks very much for your help.

You are most welcome.