Check https://www.intechopen.com/books/probiotics-and-prebiotics-in-human-nutrition-and-health/biosynthesis-of-vitamins-by-probiotic-bacteria

Also check https://www.nature.com/articles/s41598-020-64038-9

https://www.nature.com/articles/s41598-020-64038-9

Hope this will helpful

The dietary intervention of various in situ vitamins producing LAB is a benign approach to overcome such deficiency. The use of such microorganisms is also an economically viable alternative to fortification with chemically synthesized pseudo-vitamins. This indeed allows the production of foods with enhanced levels of vitamins that are rare to cause side effects. Cobalamin is most preferably produced by industrial microbial fermentation, as chemical synthesis is very costly. However, cheap agro-byproducts are most preferable as raw materials for such fermentations. A whey-based liquid medium has been utilized for the production of vitamin B12 from Propionibacterium freudenreichii 2067. The identification of biosynthesized vitamins from natural or over-expressed LAB strains can assess by spectrophotometrically and chromatographic (HPLC) techniques depending on the type of vitamins. Kindly check the following RG link:

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