https://www.academia.edu/.../Curcumin_nanoparticles_preparation_c...

Hello,

These article might be helpful to prepare curcumin nanoparticles.

https://www.ncbi.nlm.nih.gov/m/pubmed/21322563/

https://pubs.acs.org/doi/abs/10.1021/jf104402t

All tests that have been performed on humans with curcumin have shown that when used alone, curcumin is very quickly eliminated by the body. Piperine (present in black pepper) is able to inhibit curcumin removal pathways, and thus multiply its bioavailability by a factor of 20. Turmeric extracts highly concentrated in curcumin are therefore sometimes associated with Piperine. pepper to improve the bioavailability of curcumin and are proposed as a dietary supplement to contribute to the general cellular protection or in physiological situations of articular genes.

A combination of 3 g of curcumin and piperine equates to a consumption of 1 to 10 kg of turmeric per day, and increases the blood level of curcumin to a level that damages the DNA of cancer cell lines (HepG2), in tests in vitro, which can play a dual role both positive (self-destruction of cancer cells) and negative (carcinogenic / oxidative) at these very high doses

T. H. Al-Noor I am not able to open the link you shared. Can you please send me title of the paper.

Thanks.

I want to prepare high quantity of Curcumin nanoparticles, I need to prepare some complex molecules with curcumin nanoparticles I look many papers I can't find any possible methods. any suggestions.

Thanks in Advance.

Naveen.