Drug release study requires taking absorbance of samples at absorption maxima (Lambda max) of drug. What should be the approach in case of poly herbal formulation (nanogel). There are atleast 5 active components in the nanogel with different absorption maxima.
In this case, at what lambda max should the absorbance be taken?
Jagmohan Sharma
Use flash chromatography and analyse the fractions by any other suitable chemical and/or analytical method.
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Djaafar Zemali
The active substances from plants are initially extracted using appropriate solvents. It is followed by the use of methods of purification and separation .
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Ashwin Vyas
you can use HPLC with program sequence of diffrent lamda maxima & can anlyze the release quantity of drug.In primary stage you have to validate your method.
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