When administering eye drops to experimental mice, the mice often use their paws to wipe off the medication immediately after instillation. This could reduce the effectiveness of the treatment or make the results unclear.
I would like to ask if you have any methods or suggestions to prevent this issue and ensure proper absorption of the eye drops.
Thank you very much for your assistance.
Hello!
I have some experience with laboratory rabbits. When putting eye drops in the eyes, holding the animal in your arms helps avoid this problem. Also, gently pressing it down with your hand on the table surface helps, since the animal in this position cannot use its front paws. When working with restless animals, careful swaddling helps. In general, various types of gentle holding can be useful.
Perhaps these techniques can be applied to laboratory mice as well, but be careful, because mouse can bite you, which rabbit do much less often.
Vladimir
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