Why am i not getting solid after reacting APTES with salicylaldehyde?

The reaction of APTES with salicylaldehyde in ethanol leads to the formation of imine compound yellow solid which is mention in literature, but I am not getting yellow solid I don't know why? when...

28 February 2021 2,955 2 View

Why gel electrophoresis is taking too much time to run ?

I am working with TBE buffer and prepared 1% agarose gel. Previously it was taking around one hour to run but now two and half hours. I have increased the voltage from 90 to 110 but this also helped.

08 December 2020 7,416 5 View

What are the recent research topics in field of Soft Robotics based on AI and ML?

I am working in the field of practical robotics since last five years and got acquainted with AI and ML recently. I know Python and learning AI and ML using python from different sources. I want...

24 October 2020 793 6 View

Can Solar Energy take part in fighting against COVID-19?

Can "Solar-UV-cellular-damage" be an effective method to disinfect water bodies against COVID-19 in countries with a hot climate?

10 May 2020 2,556 12 View

While performing energy minimization step in GROMACS I am getteing following error. Can anyone help with this minimization problem?

gmx mdrun -v -deffnm em Back Off! I just backed up em.log to ./em.log. Running on 1 node with total 8 cores, 16 logical cores Hardware detected: CPU info: Vendor: GenuineIntel Brand:...

11 March 2020 2,902 1 View

What is iodine number in terms of activated carbon? What are the effect of iodine number on activate carbon porosity ?

11 March 2020 5,239 3 View

How to convert Netcdf file to ASCII data file?

I want to convert NetCDF file containing MODIS LAI data into ASCII file but not getting enough help from google search. if anybody is familiar with this, please give some inputs.. I am using R and...

18 February 2020 6,100 5 View

HI, Can I engineer any immortal human T cell line with the murine TCR of Ovalbumin ? Just like OT1 mice T cell have the same receptor ?

I am planning to develop a Human T cell line having the potential to kill OVA expressing tumor lines. Mostly we have to take out Tcells from OT1 mice which is expensive in overall cost. If I...

25 December 2019 3,417 2 View

What is the best suitable High Voltage amplifier to excite PZT ceramic C-91 patch (fuji ceramics ltd.)?

I need some information regarding a suggestion for piezo linear amplifier/High voltage amplifier suitable to operate at a peak voltage of 500V/mm for piezo ceramic patches (Rectangular C-91)....

27 November 2019 8,466 8 View

How we encapsulate vitamin-D with chitosan nanoparticles and how much conc. of ethanol we use to dissolve vitamin-D ?

We are trying to encapsulate vitamin-D in chitosan. Kindly suggest me the solubility of vitamin-D in ethanol and the simplest method to encapsulate vitamin-D. Thanks with regards

05 November 2019 9,341 1 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

Chlorinated organic formation in odor control scrubbers using hypochlorite?

I'm involved in a study of odor control technologies for municipal wastewater treatment plant. One of the control options involves a chemical 2-stage (acid/alkaline) packed bed scrubber. The...

03 March 2021 3,661 2 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

Why almost every element would be metallized in sufficiently high pressure and low temperature?

(This statement is from wikipedia, BTW). What is so special about metallic bond that is limiting high-P low-T state of a matter (as long as individual atoms exist, not white dwarf of neutron star...

02 March 2021 3,309 2 View

Ester cleavage conditions?

Hi all, I need to cleave the ester in Ethyl 2-amino-1H-imidazole-5-carboxylate to make the carboxylic acid and retrieve the product from solution to use in downstream applications of linking to...

01 March 2021 8,766 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

Any research papers for extraction of nutrient deprivation on macroalgae? Analysed by HPLC-UV and GC/MS. Possibly from macroalgae genus Rhizoclonium?

I am doing my thesis on the nutrient deprivation on the macroalgae Rhizoclonium sp. I will be analysing the levels over a period of roughly 5 days by HPLC-UV and GC/MS. I will be using seawater as...

28 February 2021 6,477 1 View

How to remove DCU and HOBT from my reaction?

I am doing a acid and a chiral amino alcohol reaction using DCC and HOBT in DCM or THF? Can anyone suggest me how to remove DCU and HOBT from a reaction mixture??

28 February 2021 2,153 1 View

Necessary tube lenght to cool Natural gas in a dry-ice cooling bath?

I have a tank which contains natural gas at 250 Bar and 293 Kelvin. I want to cool the gas in a dry-ice cooling bath to about 195 Kelvin. The gas will flow in a copper-tube through the bath with a...

27 February 2021 8,128 1 View

What is the most common number of epitopes in an multi-epitope Vaccine?

hi everyone, I'm interested in the field of vaccine design specifically multi-epitope cancer vaccines , I want to know if there is a minimum and maximum number of epitopes we could use in a...

27 February 2021 3,882 3 View