We are trying to formulate Albendazole suspension (for animals) using different suspending agent, the formula also contain wetting agents (propylene glycol + polysorbate 80), buffering agent, preservative and simethicone. Our issue is that always the appearance of the suspension look non-homogenize, when you steer manually you can see something like shadows in the surface. We do homogenization for enough time but still these shadows persist. We are suspecting on the suspending agent, we tried different ones, xanthan, povidone k90, HPC, HPMC, Veegum. In all formulas shadows appear with different intensity. comparing to reference product from Germany which shows NO shadows at all.
Please suggest any technique or material to be used!!
Xanthan gum is a chemical that is utilised in the production of several foods and pharmaceuticals. It has a variety of impacts in these goods, including the ability to enhance thickness, maintain textures from altering, and keep ingredients in place. Xanthan gum can be present in a variety of medications.@It's a thickening that's used in soups, sauces, gravies, drinks, syrups, relishes, and toppings. It's also utilised as a suspending agent in a variety of dishes such sauces, cake mixes, and batter. The concentration of xanthan utilised in most culinary applications is less than 0.5 percent (w/w).
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