If a have a sequence of a multi-pass transmembrane protein and I would like to see how this sequence will be translated and folded across the cell membrane, what would you recommend? Thank you so much in advance, I'm new in the field and would appreciate any kind of suggestion.
Rob Keller
Dear Parinda Limprasert Not sure what you are aiming for, but I guess a nice starting point is (when you basically only have the primary sequence) trying: CCTOP (https://cctop.ttk.hu ).
Article CCTOP: a Consensus Constrained TOPology prediction web server
For way more tools, see https://bip.weizmann.ac.il/toolbox/structure/2d.htm and scroll down to “Membrane Protein and Signal Peptide Prediction”
Best regards.
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