For Hypersonic Flows over say Mach 8, we can use Newton Theory (A local surface inclination method ) for Rough Estimate
From Newton Theory, we directly get Cd = 1; It is independent of Mach and simply assumes High Hypersonic Machs. The Formulation is attached.
For more accuracy you can use the Modified Newton theory, obtain the Cp and use the Cp to get the pressure distribution or directly the Drag.
I can assure you that you cannot use other surface inclination methods like tangent wedge and tangent cone methods. As the shock will be detached in sphere
For Research Stuff
Hypersonic flow past a sphere
Proceedings of the Indian Academy of Sciences - Section A
I agree with Aditya but since you are using CFD codes to evaluate Cd you can't be direct like the local inclination methods. Obtain the surface pressure distribution and then the surface pressure coefficient from it. Numerically integrate it taking infinitesimally small strips. Non dimensionalise it with base are and viola!!! you have the coefficient of drag