The dependency of the significance level and sample size is well recognised in medical research, where the sample size is often decided by a researcher. In economic research the sample size is often given and cannot be changed. It is well noted that testing the same hypothesis with different sample sizes leads to different results, i.e. in cases of small sample size (e.g. below 100) p-values indicate lower significance. If we use the same cutoff for p-values, then the estimation with small samples yields fewer rejections of the Ho (no relationship between independent and dependent variables) than the same estimation with big samples. Thus, small sample may mean often no relationship, whereas big sample is associated with better chances to define relationship with acceptable level of significance. This sounds not consistent. P-value cutoff should take into account the sample size and keep the balance between type 1 and type 2 errors.
How to do this? Please share respective literature and your opinion.