I have six lot each one contain 10 invertebrate larvae and a concentration of toxin. at the first concentration I have 0 dead individual the 2nd conceentration 1 dead, the 3rd 0 dead the 4 th 0 dead, the 5 th 1 dead and the 6th 3 dead.
how could I calculate the the median lethal dose?
Fit a logistic-type model and derive the LDx from it. A similar example can be found here using dose.p https://www.rdocumentation.org/packages/MASS/versions/7.3-54/topics/dose.p
Note that you probably can't get a LD50 for your data as the response only reached ~30%, but you may be able to get a LD10
Agree with Gerard Ricardo you can predict lethal dose using probit analysis technique.
You can use binomial logistic regression to get LD 50 values .
LD 50 values can be assessed from the best fit curve from the collected sample points
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