The research is based on medical domain aiming to find Epileptogenic Zone in drug refractory patients. The study uses already recorded Scalp EEG and MRI of patients for analysis to find the Epileptogenic Zone. I was thinking of considering 50 patients data for this study, but how do I justify this number?
Hi,
You can an idea about alpha value, power, effect size, and parameter estimates from published studies. From this, you can calculate sample sizes if the design and conditions appear similar.
Alternatively from the available data, you can calculate the above values and further
You can an idea about alpha value, power, effect size, and parameter estimates from published studies. From this, you can calculate sample sizes if the design and conditions appear similar.
Alternatively from the available data, you can calculate the above values and further improve in future studies
Just do the review of literature and find proportion/ Mean /SD , desired power (80% usually), Type 1 error(usually 5%)and add them in the calculator
Sample Size Calculator for Estimating a Proportion (statulator.com)
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