How to calculate measured isotope pattern (msigma) for m/z?

06 July 2023 0 1K Report

I did UPLC-QTOF-MS/MS I got the mass for every compounds and I calculate the error of mass in term of ppm, and would like caculate mSgma.

Badges
Science topic

Similar topics
Social Psychology
Attitude

More Abdeen Elkhedir's questions See All

How to formulate Albendazole suspension using Xanthan gum or Veegum as suspending agent?

We are trying to formulate Albendazole suspension (for animals) using different suspending agent, the formula also contain wetting agents (propylene glycol + polysorbate 80), buffering agent,...

22 December 2021 6,416 1 View

How to simulate a rigid member for torsion in ETABS software?

i am trying to simulate the flat slab with equivalent frame method with ETABS software to conduct the pushover analysis, for modeling the rigid torsional member I adjust the torsional constant...

05 October 2021 8,643 4 View

If we have Flavonoid with tow sugars moiety in 6 and 8 carbon both of them in form of C-bond , Which one will fragmented first C-6 or C-8?

The fragmentation of Aglycone C-Di glycoside in negative ion will produced complicated ions, so for identification such compound we need fellow the behavior of the fragmented ion in term of priority,

20 October 2019 8,048 2 View

How can I calculate the electrostatic potential GRADIENT between two points with Gaussian 09 and other programs?

I use Gaussian 09 and Multiwfn to calculate and plot the electrostatic potential, electron density and electron density gradient between any two points within the molecule. I've a trouble doing...

13 June 2019 6,138 0 View

ISO 7730 standard ?

Anyone could send me a soft copy of this standard: ISO 7730:2005 Ergonomics of the thermal environment -- Analytical determination and interpretation of thermal comfort using calculation of the...

10 February 2019 6,479 0 View

Is it mandatory that loaded nanoparticles should shows sustain release of the loaded drug?

If our nanoparticles showed enhancement of the activity of the loaded drug (lower MIC than the free antibiotic) , but its not showing sustain release when using dialysis tube method, also it is...

05 October 2018 4,546 8 View

How could I assign a weight factor to multi-objective function in optimization problem ?

I am trying to optimize the design of some object with minimizing the operation energy and discomfort hours as objective function. But the used software only solve one-objective problem, so I have...

18 September 2018 2,081 11 View

Variation in the result of assay of hydrochlorothiazide in bulk and tablet containing Amlodipine+Valsartan+hydrochlorothiazide?

manufacturing procedure: Slugging of Amlodipine + Valsartan+(binder & disintegrante) then crushing and adding hydrochlorothiazide with other excipient as extra dry granulation then...

31 January 2018 6,619 3 View

How can i formulate highly moisture absorptive active ingredient?

a Formula of anti-hypertensive drug ,very poor water solubility the formula contain sodium hydroxide+meglumin+mannitol we tried wet granulation by using 70% ethanol dissolved in it sodium...

24 August 2016 4,078 4 View

Can I use western blot data for protein of interest without normalization to the endogenous control (B-actin)?

specially when all data (including IHC) are consistent with each other unless they r normalized to B-actin.

08 September 2015 544 4 View

Can you connect an HPLC to a Mass Spec only at a certain time point?

Can anyone explain this method? Especially the last statement where it says only at 1.5 to 2.5mins was the MS/MS connected to the UPLC. How is that possible, is it a feature in this specific...

11 August 2024 8,141 3 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,403 2 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View

Where to find a gene list for CRISPRa/i library screening of regulatory factors that affect pathogenic Th17 differentiation in PBMC?

I want to perform a CRISPRa/i library screening for candidate regulatory factors that affect pathogenic Th17 differentiation in PBMC. But I am wondering how to define the size of gene library, so...

31 July 2024 2,150 0 View

Hello dear researchers. I would like to know what is a normalized mass in an EDX analysis?

EDX analisys

31 July 2024 5,947 2 View

Gas chromatography RT detection?

I am working on algal extract to which gas chromatography (Not GC-MS) spectrum I want to discover. My question is can we identify specific compounds using retention time if I compared the RT with...

29 July 2024 8,034 4 View

MAGeCK Plotting Error: Logarithmic Axis Must Have Positive Limits?

I have been running a MAGeCK test command on the terminal for a CRISPR screen to rank sgRNAs and genes based on the read count tables. However, I get only the plot of the top-ranked genes...

28 July 2024 9,811 1 View

Screening of EPS producer LAB?

if you have MRS broth already prepared, what is the manner you will follow for preparing hyper-sweet medium for screening of EPS producer LAB? what the concentration of saccharose or glucose you...

26 July 2024 6,606 0 View

Could international experts in media and journalism, AI, communications and international communication share this conference link?

"Integration of Mass Media and Communication into the System of International Relations: Place, Role, Actuality and Prospects: Modern Media Issues 2024" Website: https://immcir.alnoor.edu.iq/

23 July 2024 3,139 6 View

Why methanol and sulphuric acid used in the analysis of polyhydroxyalkanoates (PHA) by GC-MS?

Why methanol and sulphuric acid, used in the analysis of polyhydroxyalkanoates (PHA) methyl esters by GC-MS? Additionally, why do we typically use non-polar solvents in GC-MS?

22 July 2024 1,210 2 View