We have data from Finapress NIBP system recorded through the bitscope easy software for 30 min. We wish to perform an ultra short term blood pressure variability. Could anyone suggest possible tools/methods/literature about the same?
Hi Apar,
you can use this data for univariat and bivariat analyses. Univariat analyses exploit only the beat-to-beat blood pressure (most often systolic BP). The applied processing schemes resemble very much the analysis strategies that are applied for heart rate variability analysis (see e.g. Article Noninvasive measurement of blood pressure variability: Accur...
; this is just one example with a methodological focus; there are many articles, which calculate blood pressure variability parameters in specific applications). Bivariat analyses refer to baroreceptor sensitivity, i.e. the interdepencency of heart rate and blood pressure variability on short time scales (Article Comparison of various techniques used to estimate spontaneou...
).Greetings, Sebastian
Hi Apar,
In addition to what Sebastian has mentioned, always start from the research question, otherwise you'll be lost among several indexes of BP variability which have different underlying physiological mechanisms.
I have asked similar questions before and the discussion may be helpful
https://www.researchgate.net/post/How_to_perform_spectral_analysis_for_blood_pressure_variability
https://www.researchgate.net/post/How_to_perform_transfer_function_analysis_of_respiratory_and_cardiovascular_time_series
The beatscope software can give you beat by beat systolic and diastolic blood pressure and some other parameters like the beat time, etc but pay attention that the time of the beat in beatscope is diastolic time not systolic and this may matter when you want to perform baroreflex analysis. If you have simultaneous ECG I recommend to use ECG instead of pulse to extract beat times for baroreflex analysis. If you needed help in performing baroreflex analysis let me know we had several experiments with such measure as the outcome and developed MATLAB algorithms for processing blood pressure signal and performing baroreflex analysis.
Good Luck
Ali
There are various telemetry devices from datasci.com that can measure BP, ECG, or both. The associated analysis application computes variability.
I agree with Ali Gholamrezaei : please specify what do you mean by ultra short term. There are certain frequency ranges, in each of them you have different physiology. The highest (0.3 Hz in humans) is respiration-related due to purely mechanistic action, but with some component of cardiac related activity from baroreflex, Bainbridge effect etc etc.
The next range is more related to vascular activity: 0.1 Hz in humans and 0.4 Hz in rats. And below that you have all the behavioural activity related to posture-driven changes, although some authors attribute this dynamics to thermoregulation, mitochondrial peaks and many more. See e.g
Article Linear modelling analysis of baroreflex control of arterial ...
especially Fig 3 for clarification of different frequency ranges in rats after sinoaortic denervation.
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