Endogenous (self - burst) wound healing in patients with impaired metabolism, seeks for attention on many factors like tissue perfusion, peripheral neuropathy, tissue oxygenation, etc. whereas in induced diabetic models and excision wounds vascular and nerve supply are not compromised as same as in humans.
It is seen that other local and systemic factors like, hemoglobin, nutrition, limb activity, digestion etc. are not being focused in experimental studies.
In a nutshell, traumatic and atraumatic wounds, excision/incision and self burst wounds follows different healing methods.
The medicaments showing positive outcomes in excision models of diabetes induced Wistars should not be blindly followed without focusing on other healing factors.
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
Depends on model Because main cause for plantar diabetic foot ulcers is pressure imbalance & cure is pressure balancing
I agree 100% with Dr. Laborde especially with the first of 14 responses.
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