so I am working on insilico drug discovery and I am seduced by the situation where I have to select a plant or algae for use in this drug discovery work for diabetic patients.
I Want history details of public goods with reference to world, India and gujarat. Please help if anyone can.
30 October 2020 726 2 View
In general, are item specific (IS) response options better than agree/disagree (A/D) Likert scale response option in terms of reliability, validity and quality? I am looking at it from the...
27 October 2020 3,853 8 View
I have un-replaceable tissues to process for several experimentation such as MS/ WB/ IHC etc. However, I suspect the direct contact of liquid nitrogen to my samples for the duration of few...
18 October 2020 9,375 3 View
I mixed 60 vol% boron carbide (B4C), 25 vol% titanium diboride (TiB2), 10 vol% silicon carbide (SiC) and 5 vol% alumina (Al2O3) powders in jar mill for 12 hours using toluene as mixing...
17 June 2020 1,433 13 View
For academic purpose, free and open source simulation tool for internet of things
09 April 2020 7,137 11 View
Hello Sir, So i have a foam based temporary prototype of a component which i want to be 3d printed. I wanted to make a cad model of it via solidworks or catia but it is too complex to model. If I...
28 February 2020 4,193 2 View
I am working on detecting and discriminating oil spill on ocean surface using full polarimetric SAR images. Since the freely available SAR data with a confirmed oil spill is very limited, I am...
06 February 2020 9,960 3 View
I've done M.Sc in Applied Psychology and I've been applying for PhD Clinical Psychology for more than 1.5 years in a lot of universities in India but my research proposals get rejected because I...
19 January 2020 7,773 10 View
I have frequency dependent complex conductivity data of a strongly correlated material. Since, scattering rate and effective mass of the charge carriers are frequency dependent in correlated...
01 January 2020 5,634 1 View
20 November 2019 9,478 1 View
We found tests to determine cardiovascular risk taking into account lipid profile, blood pressure, age, history of diabetes, other laboratories. But when weight is involved, there is a paradox. I...
02 March 2021 6,036 1 View
I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...
02 March 2021 8,437 2 View
I am doing my thesis on the nutrient deprivation on the macroalgae Rhizoclonium sp. I will be analysing the levels over a period of roughly 5 days by HPLC-UV and GC/MS. I will be using seawater as...
28 February 2021 6,477 1 View
Hi all I am working on colon-targeted drug delivery for which I kept mice fasting for 6h using fasting grills during scotophase (dark period). I observed liquid fecal content in the cecum and...
23 February 2021 7,701 2 View
Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...
23 February 2021 7,429 1 View
Hello, I have run into an issue that has sparkled a debate at work: is the LLOQ/ULOQ impacted by injection volume under the following circumstances: 1) Same dilution factor of all samples 2)...
23 February 2021 9,159 3 View
Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...
23 February 2021 8,155 5 View
I am planning to work on T2 diabetic animals and check the efficacy of probiotics. My initial plan is to fed B6 animals with HFD for a while. But now, I have the chance to work on ob/ob mice. My...
18 February 2021 6,896 3 View
We are looking into utilizing alginate as a gel coating on an HDPE substrate for drug delivery. I would like to ask the community about their experience with alginate and which commercial sources...
15 February 2021 4,319 4 View
I'm working on gram negative i want to use any natural extract (plant extract) or triple drug combination against its biofilm formation.
14 February 2021 1,403 3 View