I wondered if cell age limits our choices in choosing a cell for a specific application in tissue engineering ? like neural tissue engineering for instance
for sure age affect proliferation and differentiation capabilities of adult stem cell, nevertheless there are few adult progenitors population less influenced by ageing likewise pericytes.
There are a lot of studies which have shown the effect of ageing and senescence on stem cell potential in term of proliferation, differentiation . You should also consider ageing of cells during pass ageing as well as age of donor.
Do you mean the age of the cell when it is isolated (age of the patient) or the nombre or passages in vitro? And what choices are you talking about? This is very vague!!