A number of studies say they "predialyzed" albumin to remove contaminants but none explain how this is done. I would be very grateful to know what predialysis decontamination protocols have worked in your experience.
The article "Virulence Factors of Escherichia coli Contribute to Acute Renal Failure" states that "The perfusion medium was supplemented with predialyzed (3 x 3 h) bovine serum albumin (60 g/l)". I don't know what the 3 x 3 h notation means but if anyone can parse it that would be one predialysis protocol potentially?
Dear Alexander,
thank you for sharing this interesting technical question with the RG community. In this context please have a look at the following potentially useful article which might help you in your analysis:
Quantification of the difference between pre-dialysis and post-dialysis serum albumin measurement and its relationship to intra-dialytic weight gain
Article Quantification of the difference between pre-dialysis and po...
Fortunately this paper has been posted by the authors as public full ext. Thus you can freely download it as pdf file. For a different view on the issue please also check the following study:
Pre-dialysis serum albumin is a poor indicator of nutritional status in stable chronic haemodialysis patients
Article Pre-dialysis serum Albumin is a poor indicator of nutritiona...
Good luck with your work!
re Frank: Both of those are looking at albumin before dialysis in patients, not predialyzing commercial albumin to remove contaminants, if I understand correctly
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