Hi, I want to create a layer of PEGDA onto a U-shaped PMMA surface. The hyrogel formation works well however the PEGDA layer once set is moving within the PMMA wells as it is not bonded to the PMMA surface. Has anyone any suggestions tp promote bonding? It needs to be biocompaitble as there will be spheroids maintained in the PEGDA coated wells.
Thanks
Dear Finola Cliffe
As far as I understand the question, it's clear to me that you need to stand on chemical approaches based on grafting concept to immobilize hydrogels on surfaces. The recent review by Mengjing Fu and et al., titled "Recent advances in hydrogel-based anti-infective coatings" is very helpful as you can request from the authors on the following RG link:
Article Recent advances in hydrogel-based anti-infective coatings
Best regards
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