How do I measure the Surface layer thickness(Surfactant layer) in Drug nanocrystal suaface?

Can Anyone, help me determination of Surfactant layer thickness in nanocrystal surface. please provide literature for support.Drug Nanocrystal is water In-soluble form.

31 December 2017 2,322 0 View

How the Span in particle size distribution effects the invitro dissolution?

08 September 2017 480 1 View

How to prepare 30 mM of acetate buffer solution ( Sodium acetate + Glacial acetic acid)?

how to prepare 30 mM of acetate buffer solution ( Sodium acetate + Glacial acetic acid)?

04 May 2017 4,127 3 View

How to measure zetapotential for Iron complex injectable formulations ?

How to measure zetapotential for Iron complex injectable formulations?

04 May 2017 3,634 1 View

How to set the absorption index in malvern master 3000 for nanosuspension?

How to fix the absorption index for nanosuspension in mastersizer for particle size development.

02 March 2017 8,840 0 View

How to measure the specific surface area for the nano crystal particle?

02 March 2017 7,283 0 View

How to get desired particle size of an parenteral nanosuspension?

currently am developing parental nano suspension by using media milling process but the problem is am unable to achieve the desired particle size range and in my formulation am using tween as...

10 November 2016 295 10 View

How to select the molecular weight cutoff membrane filters from Ophthalmic emulsion in vitro release studies?

i am preparing ophthalmic nano emulsions to prove the in vitro release fro formulation. i need to select the proper MWCO membrane.will it depend on the Molecular weight of drug molecule or any...

08 September 2016 5,812 7 View

An anyone suggest how to estimate drug distribution in all the phases of a oil-in-water nanoemulsion?

01 January 1970 3,509 12 View

Discrete Phase model (DPM) particle break-up has particle size limits during particle tracking?

Hello, I am currently working on simulating water droplet partciles in a closed room. When I use uniform particles, without "particle break-up", I can carry out the simulation without any problem....

02 March 2021 3,053 2 View

Distribution of particles in metal matrix?

How would define the "good" and "poor" distribution of particles within the matrix. Is there a quantitative solution to assess the distribution of the particles, which then having denotation of...

28 February 2021 7,397 8 View

Is there a deep reason for using the squared modulus of the wave function as the probability density of the existence of the particle?

I think we were all surprised at the first time we got to know quantum mechanics that the squared modulus of the wave function is the probability density of the existence of the particle? The role...

28 February 2021 6,282 9 View

Zno nano particles colour changed from white to grey in process of calcination any suggestions?

In the formation of Zno nano particles process, after drying at 120 degree C, my zno nano particles are completely white but when i calcine it for 450 degree C it converts into grey colour. i...

26 February 2021 2,435 4 View

Why there are two peaks while using the mie plot of Silver nanoparticle?

Hi, I am trying to learn the theoretical modelling of silver nanoparticle using the Mie scattering theory. After that, I discovered a software named Mieplot developed by Philip Laven, where it...

25 February 2021 7,493 6 View

Questio regarding micro/nano particles fabrication ?

I will start to fabricate micro/nanoparticles for growth factor release and I check out a procedure quite nice, however, it is lacking some details and since I don't have much knowledge doing this...

20 February 2021 199 2 View

Why is my pressure equal to kinetic energy in NVT MD simulation?

I don't know much about molecular dynamics, but I am suspicious of my pressure being equal to kinetic energy. I am using // sum the velocities squared: double v2sum = 0.0; for (int i = 0; i

15 February 2021 1,316 3 View

How complex systems physics/statistical mechanics would be helpful for particle physics & Networking?

Recently, I've been selected for an ICTP program named Physics of Complex Systems. But, I have a keen interest in Particle Physics & Quantum networks. As statistical mechanics involved in...

11 February 2021 699 3 View

What is the structure of a photon that can describe the interference experiments that reject the wave nature of light?

De Broglie's double-solution postulated a causal model of Quantum Mechanics. Knowledge of the photon structure was needed to model the particle part of the cause of the Double Slit interference...

11 February 2021 6,869 5 View

How can I take subsamples of water from a larger sample in a way that allows me to measure the iron content of the subsample?

I learned how to take subsamples with a magnetic stir bar, but I noticed iron particles stick to the bar, and I am having trouble finding a standard method to solve that problem. How can I take a...

04 February 2021 4,778 1 View