First of all, when we talk about nanoparticles in general there is mainly two types :

1- Biodegradable NP

2- Non biodegradable NP

the problem is not come out from using the biodegradable NP but rather come when the type of the pesticides incorporated inside these NP. The finale fate for Biodegradable NP is being secreted from the body as inert and degrade without harming the body but for the pesticides or fertilizers will have an accumulation effect over time and their accumulation effects will appear as PPM (concentration ) or (PPB) over a long time.

The idea of using NP is to incorporate the less amount of pesticides or fertilizer which can give effects over a long period of time instead of conventional type of fertilizer which may have a large quantity of it but less beneficial effect and more accumulating side effect in our bodies.

From my reading and experience in this issue, Antioxidants are the best for removing the heavy metals (HM) from the body but this takes a long time.

It is documented that Curcumin, Cinnamon, Basil leaves, Mary gold, Ginger, Chamomile flowers, Wheat germ, Sesame oil, Olive oil as well as Vitamins A, C and E can do the job.

However, their new from (Nanoparticles), I assume that there is no available confirmed study on their possible removal from the body as this is a new area of research.

Hi

you can use bio surfactance like oleic acid. it for avoid agglomeration of particles.

best