Hardy - Weinberg equilibrium for genotype and gene frequencies , found essential factors affecting gene frequency , including :
1- systematic factors , which affect gene frequency and we can predict the quantity and direction of changing , these factors , selection , mutation , migration.
2- Dispersion factors , including the affect of chance , affect gene frequency and can predict the quantity but not the direction of changing .
The conditions and rules of these principles must be in large ( hundreds rather than tens ) random mating population .
Natural selection changes allele frequency by selecting against alleles that reduce the chance of survival and selecting for alleles that enhance the chance of survival.
Phenotypes with a range of expressions in a population, from common to extremes, are subject to selective pressures. Directional selection chooses for one extreme or against one extreme of a phenotype. Disruptive selection chooses against the average phenotype, leaving different extremes of a phenotype in the population. Stabilizing selection chooses against the extreme phenotypes in the population, leaving the average phenotype.
Thank you Khalid and Temim, I will look at the theories of Fisher, Wright and Haldane again soon. One thing that I also need to follow in closer detail is the relationship between the early theoretical models and the experiments that were run by Lande (1979) and Lande & Armold (1983). I am surprised that I have seen so few papers that use formulae to express immigration and emigration as a source - sink dynamic.
I have not given up attempting to answer my own kaleidoscope question (roughly 24 of them) but it does seem that the paradigms really shift as I try to answer each one. When I get through these questions, I will need some second opinions.