It is a parasitic gene amplified from a village, I have expressed the mutations as haplotypes.
If i make a phylogenetic tree, will I be able to interpret any mutations or will it be possible for me to suggest that the gene is subjected to mutation etc using the tree.
Or is there any other method/way to represent this in a report
Regards.
Ansel.
Dear Ansel
Interesting! You could fine map the haplotypes using evolutionary trees. Pl use Sweep tool from Braod institute or http://itol.embl.de/
Best
Prash
Hi,
I do not understand the question, but if you mean you want compared a polymorphism were using two different area? IF is the same class of its genome can pass but if is at a gene and the other at a microsatellite this is not possible because the two regions does not accumulate mutations in the same manner.
Thank you for the responses. I will try it out
@semir, The gene is a normally conserved gene, mutations were seen at the gene sequence only but of the same area. (earlier reports have shows that 2-3 allelic variants are present in this village)
Regards..!!
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