How do I perform a biocatalytic oxidation of alcohol to acid?

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Can anyone suggest me about separation of secondary amine from a mixture of primary and tertiary amine?

I want to know about Selective separation of secondary amine from a mixture of primary and tertiary amine of long chain carbon atoms having high boiling points (boiling point range is 200 to 280oC

06 July 2018 9,916 0 View

Can anyone providing me necessary publications on determining stability of Radiolabeled APIs?

How to determine the stability of Radiolabeled APIs?

01 February 2018 9,942 0 View

Can anyone suggest me regarding specific technique for biocatalyst immobilization ?

I want to immobilize Nitrile hydatase which is in isolated form to convert Nitrile to Amide.

02 March 2017 6,434 7 View

Can anyone suggest a good sodium dithionite workup after reduction a nitro function?

The reaction carried out in aqueous condition, after completion of the reaction diluting the reaction mass with water, and also tried with basic work up, but crucial is that there is a base...

04 May 2015 8,084 3 View

What is the critical parameter in the oxidation reaction by H2O2 with Na2WO4 2H2O and PTC catalyst?

We are busy in oxidation of a long chain aliphatic alcohol to acid by H2O2 with catalytic quantity of Na2WO4. 2H2O and PTC (Tricaprylmethylammonium chloride), but we could not see...

04 May 2015 3,094 5 View

Can anyone provide us a vendor name who can supply us N-formyl-N-methylformamide for a specific API?

We have required a chemical ‘N-formyl-N-methylformamide’ for a specific API . We haven’t found any supplier who can supply this chemical to us in our region. Can anyone inform the name of supplier...

09 October 2014 746 3 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Basis set and input instruction to calculate HOMO and LUMO using Orca for Imidazolium based organic salts?

Hey there, As a synthetic chemist delving into theoretical calculations for my imidazolium-based organic molecules, I would greatly appreciate any guidance on the appropriate input instructions...

09 August 2024 5,444 7 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

Determining the worth of a point improvement in Hamilton Depression Scale?

Dear readers, Thanks for your attention. I am wondering about the health economic problem of quantifying the value of interventions which a) prevent, b) improve symptom profile and c) ultimately...

05 August 2024 3,246 1 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View

Conjugation of PEG-Amine to an Amino Acid Using EDC?

I am attempting to conjugate PEG to an amino acid at the C-terminus, for the purposes of producing nanoparticles. I have been told that PEG modified with amine groups can be used for this purpose,...

31 July 2024 2,033 1 View

Can we patent a process flow diagram developed using a process simulator but no actual cases is carried out?

Can we patent a process flow diagram developed using a process simulator but no actual cases is carried out? For example consider a process for certain product manufacture where a new process flow...

31 July 2024 781 1 View

How to improve peaks separation in HPLC?

Hi everyone, I'd like to better separate two close peaks coming from a bioconversion sample, I'm currently using a C18 KromaPhase 4,6mm Ø.I. SCHARLAU, particle size (µm): 10, pore size (Å): 100,...

30 July 2024 435 3 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View